Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 3/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048961 | 0.81 | DRD2 (0.40) | PRMT5WDR77NNMTPIP4K2A | |
| SCHEMBL30941032 | 0.79 | PRMT5 (0.40) | BRD4PRMT5WDR77GLSROCK2 | |
| SCHEMBL25047425 | 0.77 | PIP4K2A (0.39) | PRMT5WDR77NNMTPIP4K2A | |
| SCHEMBL30531024 | 0.77 | BRD4 (0.48) | BRD4GLSROCK2L3MBTL1CREBBP | |
| SCHEMBL3509882 | 0.77 | BRD4 (0.48) | BRD4GLSROCK2L3MBTL1CREBBP | |
| SCHEMBL25048447 | 0.76 | PIP4K2A (0.37) | PRMT5WDR77NNMTPIP4K2A | |
| SCHEMBL25047597 | 0.75 | PIP4K2A (0.37) | PRMT5WDR77NNMTPIP4K2A | |
| SCHEMBL30941316 | 0.74 | PRMT5 (0.38) | BRD4PRMT5WDR77NNMT | |
| SCHEMBL30974881 | 0.73 | GPR119 (0.38) | PRMT5WDR77ACACBNNMTKMT2A | |
| SCHEMBL29247169 | 0.73 | GPR119 (0.38) | PRMT5WDR77ACACBNNMTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |