Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | METTL3 | Q86U44 | 11/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.42 |
| ▸ | ADK | P55263 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30941639 | 1.00 | MTOR (0.53) | MTORRAB9AMETTL3CA2PRMT5 | |
| SCHEMBL30941053 | 0.90 | METTL3 (0.56) | METTL3CA2PRMT5 | |
| SCHEMBL30940751 | 0.90 | METTL3 (0.54) | METTL3CA2PRMT5ADK | |
| SCHEMBL25046806 | 0.90 | METTL3 (0.54) | METTL3CA2PRMT5ADK | |
| SCHEMBL25048821 | 0.90 | METTL3 (0.56) | METTL3CA2PRMT5 | |
| SCHEMBL30941506 | 0.90 | ADK (0.40) | MTORRAB9AMETTL3CA2PRMT5 | |
| SCHEMBL25048825 | 0.89 | CA2 (0.52) | METTL3CA2ADK | |
| SCHEMBL30941348 | 0.89 | CA2 (0.52) | METTL3CA2ADK | |
| SCHEMBL25048822 | 0.88 | METTL3 (0.49) | METTL3CA2PRMT5 | |
| SCHEMBL25046807 | 0.88 | METTL3 (0.52) | METTL3CA2PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |