Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2A | P48426 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ADCY5 | O95622 | 3/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21130182 | 0.87 | PIP4K2A (0.40) | PIP4K2AACACBADCY5SLC22A12NNMT | |
| SCHEMBL19714842 | 0.86 | ADCY5 (0.48) | PIP4K2AACACBADCY5PRMT5WDR77 | |
| SCHEMBL21130022 | 0.86 | SLC22A12 (0.40) | PIP4K2AACACBADCY5SLC22A12NNMT | |
| SCHEMBL21129819 | 0.82 | PIP4K2A (0.40) | PIP4K2AACACBADCY5SLC22A12NNMT | |
| SCHEMBL29247166 | 0.82 | GPR119 (0.38) | PIP4K2AACACBSLC22A12NNMTPRMT5 | |
| SCHEMBL29247169 | 0.82 | GPR119 (0.38) | PIP4K2AACACBSLC22A12NNMTPRMT5 | |
| SCHEMBL30974881 | 0.82 | GPR119 (0.38) | PIP4K2AACACBSLC22A12NNMTPRMT5 | |
| SCHEMBL21129938 | 0.81 | PIP4K2A (0.38) | PIP4K2AACACBADCY5SLC22A12NNMT | |
| SCHEMBL25047477 | 0.81 | PIP4K2A (0.39) | PIP4K2AADCY5NNMTPRMT5WDR77 | |
| SCHEMBL29247142 | 0.79 | SLC22A12 (0.39) | PIP4K2AACACBSLC22A12NNMTPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |