Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 9/20 | 0.35 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | HCK | P08631 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30974881 | 1.00 | GPR119 (0.38) | GPR119ACACBNNMTPIP4K2ASLC22A12 | |
| SCHEMBL29247169 | 1.00 | GPR119 (0.38) | GPR119ACACBNNMTPIP4K2ASLC22A12 | |
| SCHEMBL30372589 | 0.84 | SLC22A12 (0.39) | ACACBNNMTPIP4K2ASLC22A12PRMT5 | |
| SCHEMBL29247142 | 0.84 | SLC22A12 (0.39) | ACACBNNMTPIP4K2ASLC22A12PRMT5 | |
| SCHEMBL29247145 | 0.84 | SLC22A12 (0.39) | ACACBNNMTPIP4K2ASLC22A12PRMT5 | |
| SCHEMBL30373136 | 0.83 | NNMT (0.41) | ACACBNNMTSLC22A12PRMT5WDR77 | |
| SCHEMBL29247562 | 0.83 | NNMT (0.41) | ACACBNNMTSLC22A12PRMT5WDR77 | |
| SCHEMBL25047944 | 0.82 | PIP4K2A (0.44) | ACACBNNMTPIP4K2ASLC22A12KMT2A | |
| SCHEMBL12395349 | 0.79 | GPR119 (0.46) | GPR119PIP4K2AUBA6 | |
| SCHEMBL13861581 | 0.79 | SRC (0.48) | GPR119PIK3CDABL1EGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317963-A | TRPML modulators, compositions thereof, and methods of use | 卡拉韦治疗公司 | 2024-07-09 | — | — | CN | disclosed |