Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 15/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.38 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | ADK | P55263 | 3/20 | 0.36 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30940774 | 0.85 | METTL3 (0.53) | METTL3PRMT5WDR77ADK | |
| SCHEMBL25047947 | 0.85 | METTL3 (0.53) | METTL3PRMT5WDR77ADK | |
| SCHEMBL30940846 | 0.85 | METTL3 (0.53) | METTL3PRMT5WDR77ADK | |
| SCHEMBL25048359 | 0.85 | METTL3 (0.53) | METTL3PRMT5WDR77ADK | |
| SCHEMBL25047961 | 0.82 | SRC (0.41) | METTL3FPR3FPR2 | |
| SCHEMBL31618062 | 0.81 | ADK (0.44) | METTL3PRMT5ADKRAPGEF3 | |
| SCHEMBL31617944 | 0.76 | ADK (0.44) | METTL3PRMT5ADKRAPGEF3 | |
| SCHEMBL25047957 | 0.74 | METTL3 (0.57) | METTL3ADK | |
| SCHEMBL25048440 | 0.74 | METTL3 (0.57) | METTL3ADK | |
| SCHEMBL30940749 | 0.74 | METTL3 (0.57) | METTL3ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |