Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 11/20 | 0.35 |
| ▸ | EGFR | P00533 | 4/20 | 0.35 |
| ▸ | LCK | P06239 | 3/20 | 0.35 |
| ▸ | TEK | Q02763 | 2/20 | 0.35 |
| ▸ | C1S | P09871 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 3/20 | 0.33 |
| ▸ | ABL2 | P42684 | 3/20 | 0.33 |
| ▸ | FGR | P09769 | 1/20 | 0.32 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.32 |
| ▸ | TXK | P42681 | 1/20 | 0.32 |
| ▸ | FRK | P42685 | 1/20 | 0.32 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 2/20 | 0.31 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | PRKCG | P05129 | 1/20 | 0.31 |
| ▸ | PRKCB | P05771 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | PRKCH | P24723 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048727 | 0.91 | SRC (0.35) | SRCEGFRLCKC1SABL1 | |
| SCHEMBL25047567 | 0.89 | C1S (0.36) | SRCEGFRLCKTEKC1S | |
| SCHEMBL25048943 | 0.88 | C1S (0.35) | SRCEGFRLCKC1SABL1 | |
| SCHEMBL25047541 | 0.88 | SRC (0.49) | SRCEGFRLCKTEKABL1 | |
| SCHEMBL25048047 | 0.87 | C1S (0.33) | SRCEGFRLCKC1SABL1 | |
| SCHEMBL25046690 | 0.86 | ALK (0.34) | SRCEGFRC1SGABRA1GABRB2 | |
| SCHEMBL25049217 | 0.85 | C1S (0.36) | SRCEGFRLCKTEKC1S | |
| SCHEMBL25048023 | 0.84 | C1S (0.33) | SRCEGFRC1SGABRA1GABRB2 | |
| SCHEMBL30940839 | 0.84 | C1S (0.33) | SRCEGFRC1SGABRA1GABRB2 | |
| SCHEMBL25047579 | 0.84 | EGFR (0.36) | SRCEGFRLCKC1SABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |