Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 11/20 | 0.34 |
| ▸ | AXL | P30530 | 10/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 10/20 | 0.34 |
| ▸ | FLT3 | P36888 | 9/20 | 0.33 |
| ▸ | C1S | P09871 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 5/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047581 | 0.90 | MERTK (0.32) | MERTKAXLTYRO3FLT3C1S | |
| SCHEMBL25048022 | 0.89 | AXL (0.36) | MERTKAXLTYRO3FLT3MET | |
| SCHEMBL25046677 | 0.87 | HTR2A (0.34) | MERTKAXLTYRO3FLT3 | |
| SCHEMBL25047528 | 0.87 | TYRO3 (0.37) | MERTKAXLTYRO3FLT3 | |
| SCHEMBL25048024 | 0.86 | SRC (0.35) | C1SGABRA1GABRB2SRCEGFR | |
| SCHEMBL25048916 | 0.85 | AXL (0.36) | MERTKAXLTYRO3FLT3MET | |
| Hydrochloric Acid SCHEMBL30941119 | 0.83 | GABRA1 (0.32) | ALKMERTKAXLTYRO3FLT3 | |
| SCHEMBL25048045 | 0.83 | AXL (0.33) | MERTKAXLTYRO3FLT3 | |
| SCHEMBL25048097 | 0.83 | AXL (0.32) | MERTKAXLTYRO3FLT3 | |
| SCHEMBL25047541 | 0.82 | SRC (0.49) | SRCEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |