Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1S | P09871 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 5/20 | 0.34 |
| ▸ | INSR | P06213 | 4/20 | 0.34 |
| ▸ | ABL1 | P00519 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 3/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.34 |
| ▸ | LYN | P07948 | 3/20 | 0.34 |
| ▸ | LCK | P06239 | 3/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
| ▸ | PAK4 | O96013 | 2/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.34 |
| ▸ | CSF1R | P07333 | 2/20 | 0.34 |
| ▸ | RET | P07949 | 2/20 | 0.34 |
| ▸ | HCK | P08631 | 2/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.34 |
| ▸ | MARK3 | P27448 | 2/20 | 0.34 |
| ▸ | FLT4 | P35916 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.34 |
| ▸ | BLK | P51451 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048943 | 0.92 | C1S (0.35) | C1SSRCINSRABL1EGFR | |
| SCHEMBL25048047 | 0.91 | C1S (0.33) | C1SSRCABL1EGFRLCK | |
| SCHEMBL25048024 | 0.89 | SRC (0.35) | C1SSRCABL1EGFRLCK | |
| SCHEMBL25047579 | 0.89 | EGFR (0.36) | C1SSRCABL1EGFRFGFR1 | |
| SCHEMBL25048021 | 0.86 | SRC (0.46) | SRCABL1EGFRABL2 | |
| SCHEMBL25048022 | 0.86 | AXL (0.36) | FLT3MAP4K4NTRK1KITAXL | |
| SCHEMBL25048632 | 0.85 | KCNH2 (0.34) | C1SSRCINSREGFRFGFR1 | |
| SCHEMBL25048727 | 0.85 | SRC (0.35) | C1SSRCABL1EGFRLCK | |
| SCHEMBL25048499 | 0.84 | C1S (0.34) | C1S | |
| SCHEMBL25049217 | 0.84 | C1S (0.36) | C1SSRCINSRABL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |