Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.36 |
| ▸ | IGF1R | P08069 | 3/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 4/20 | 0.35 |
| ▸ | SRC | P12931 | 4/20 | 0.35 |
| ▸ | ABL2 | P42684 | 4/20 | 0.35 |
| ▸ | LCK | P06239 | 2/20 | 0.35 |
| ▸ | C1S | P09871 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 6/20 | 0.31 |
| ▸ | DRD4 | P21917 | 6/20 | 0.31 |
| ▸ | DRD3 | P35462 | 5/20 | 0.31 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.31 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.31 |
| ▸ | HCK | P08631 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048047 | 0.89 | C1S (0.33) | EGFRABL1SRCABL2LCK | |
| SCHEMBL25048943 | 0.89 | C1S (0.35) | EGFRIGF1RABL1SRCABL2 | |
| SCHEMBL25047567 | 0.89 | C1S (0.36) | EGFRIGF1RERBB2ABL1SRC | |
| SCHEMBL25048024 | 0.84 | SRC (0.35) | EGFRIGF1RABL1SRCABL2 | |
| SCHEMBL25048632 | 0.82 | KCNH2 (0.34) | EGFRIGF1RERBB2SRCLCK | |
| SCHEMBL25048021 | 0.82 | SRC (0.46) | EGFRABL1SRCABL2 | |
| SCHEMBL25048727 | 0.80 | SRC (0.35) | EGFRIGF1RABL1SRCABL2 | |
| SCHEMBL25049217 | 0.79 | C1S (0.36) | EGFRIGF1RERBB2ABL1SRC | |
| SCHEMBL25048046 | 0.78 | PRCP (0.34) | EGFRABL1SRCABL2LCK | |
| SCHEMBL25046677 | 0.77 | HTR2A (0.34) | DRD2DRD4DRD3KCNH2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |