Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.42 |
| ▸ | EGFR | P00533 | 5/20 | 0.42 |
| ▸ | ABL2 | P42684 | 5/20 | 0.42 |
| ▸ | SRC | P12931 | 8/20 | 0.40 |
| ▸ | IGF1R | P08069 | 3/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCH | P24723 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047951 | 0.87 | ABL1 (0.57) | ABL1EGFRABL2SRCIGF1R | |
| SCHEMBL25048551 | 0.83 | ABL1 (0.43) | ABL1EGFRABL2SRCIGF1R | |
| SCHEMBL25048162 | 0.83 | METTL3 (0.46) | ABL1EGFRABL2SRCIGF1R | |
| SCHEMBL25047938 | 0.80 | METTL3 (0.44) | ABL1EGFRABL2SRCIGF1R | |
| SCHEMBL25047931 | 0.80 | ABL1 (0.41) | ABL1EGFRABL2SRCIGF1R | |
| SCHEMBL25049073 | 0.80 | ABL1 (0.41) | ABL1EGFRABL2SRCIGF1R | |
| SCHEMBL25048562 | 0.79 | ADK (0.44) | ABL1EGFRABL2SRCIGF1R | |
| SCHEMBL25048517 | 0.79 | ABL1 (0.40) | ABL1EGFRABL2SRCIGF1R | |
| SCHEMBL25048334 | 0.78 | — | — | |
| SCHEMBL25048346 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |