Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.43 |
| ▸ | EGFR | P00533 | 4/20 | 0.43 |
| ▸ | ABL2 | P42684 | 4/20 | 0.43 |
| ▸ | RET | P07949 | 3/20 | 0.42 |
| ▸ | IGF1R | P08069 | 3/20 | 0.41 |
| ▸ | SRC | P12931 | 5/20 | 0.38 |
| ▸ | LCK | P06239 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | KIT | P10721 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
| ▸ | NPM1 | P06748 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047951 | 0.87 | ABL1 (0.57) | ABL1EGFRABL2RETIGF1R | |
| SCHEMBL25047938 | 0.86 | METTL3 (0.44) | ABL1EGFRABL2RETIGF1R | |
| SCHEMBL25048562 | 0.85 | ADK (0.44) | ABL1EGFRABL2RETIGF1R | |
| SCHEMBL25048552 | 0.84 | METTL3 (0.37) | ABL1EGFRABL2IGF1R | |
| SCHEMBL25048193 | 0.83 | ABL1 (0.42) | ABL1EGFRABL2RETIGF1R | |
| SCHEMBL25048517 | 0.83 | ABL1 (0.40) | ABL1EGFRABL2RETIGF1R | |
| SCHEMBL25049073 | 0.80 | ABL1 (0.41) | ABL1EGFRABL2IGF1RSRC | |
| SCHEMBL25046669 | 0.80 | METTL3 (0.40) | ABL1EGFRABL2RETIGF1R | |
| SCHEMBL25049103 | 0.76 | ADK (0.38) | ABL1EGFRABL2IGF1R | |
| SCHEMBL25047658 | 0.76 | ADCY5 (0.33) | ABL1EGFRABL2IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |