Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30941327 | 1.00 | PRMT5 (0.35) | PRMT5METTL3WDR77MTORRAB9A | |
| SCHEMBL30941391 | 0.86 | PRMT5 (0.40) | PRMT5METTL3WDR77MTORRAB9A | |
| SCHEMBL25046728 | 0.86 | PRMT5 (0.40) | PRMT5METTL3WDR77MTORRAB9A | |
| SCHEMBL31617907 | 0.83 | — | — | |
| SCHEMBL25047680 | 0.83 | — | — | |
| SCHEMBL25047681 | 0.80 | ADCY5 (0.33) | — | |
| SCHEMBL30940836 | 0.77 | MTOR (0.35) | PRMT5METTL3WDR77MTORRAB9A | |
| SCHEMBL25046679 | 0.77 | MTOR (0.35) | PRMT5METTL3WDR77MTORRAB9A | |
| SCHEMBL25048504 | 0.76 | METTL3 (0.38) | PRMT5METTL3WDR77MTORRAB9A | |
| SCHEMBL30941135 | 0.76 | METTL3 (0.38) | PRMT5METTL3WDR77MTORRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |