Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30940836 | 1.00 | MTOR (0.35) | MTORRAB9AMETTL3PRMT5WDR77 | |
| SCHEMBL25046681 | 0.79 | FGR (0.33) | — | |
| SCHEMBL30941391 | 0.77 | PRMT5 (0.40) | MTORRAB9AMETTL3PRMT5WDR77 | |
| SCHEMBL30941327 | 0.77 | PRMT5 (0.35) | MTORRAB9AMETTL3PRMT5WDR77 | |
| SCHEMBL25046728 | 0.77 | PRMT5 (0.40) | MTORRAB9AMETTL3PRMT5WDR77 | |
| SCHEMBL25048243 | 0.77 | PRMT5 (0.35) | MTORRAB9AMETTL3PRMT5WDR77 | |
| SCHEMBL30941135 | 0.77 | METTL3 (0.38) | MTORRAB9AMETTL3PRMT5WDR77 | |
| SCHEMBL25048504 | 0.77 | METTL3 (0.38) | MTORRAB9AMETTL3PRMT5WDR77 | |
| SCHEMBL30941218 | 0.71 | ADK (0.53) | RAB9A | |
| SCHEMBL25046789 | 0.71 | ADK (0.55) | MTORRAB9AMETTL3PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |