Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY5 | O95622 | 3/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | ABL2 | P42684 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 2/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048243 | 0.80 | PRMT5 (0.35) | — | |
| SCHEMBL30941327 | 0.80 | PRMT5 (0.35) | — | |
| SCHEMBL25046735 | 0.79 | ABL1 (0.31) | EGFRABL1ABL2RETLCK | |
| SCHEMBL25046681 | 0.76 | FGR (0.33) | EGFRABL1ABL2RETLCK | |
| SCHEMBL31617907 | 0.76 | — | — | |
| SCHEMBL25047680 | 0.76 | — | — | |
| SCHEMBL25046659 | 0.74 | SRC (0.44) | EGFRABL1ABL2SRC | |
| SCHEMBL25046737 | 0.73 | ADCY5 (0.33) | ADCY5EGFRABL1ABL2RET | |
| SCHEMBL25047677 | 0.73 | ADK (0.45) | ADCY5EGFRABL1ABL2RET | |
| SCHEMBL25048763 | 0.73 | ADCY5 (0.45) | ADCY5EGFRABL1ABL2RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |