Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 3/20 | 0.33 |
| ▸ | USP7 | Q93009 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | UBA6 | A0AVT1 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047504 | 0.90 | JAK3 (0.40) | JAK3GPR119CNR2PRMT5WDR77 | |
| SCHEMBL25048843 | 0.87 | GPR119 (0.39) | JAK3GPR119CNR2PRMT5WDR77 | |
| SCHEMBL25048811 | 0.87 | GPR119 (0.40) | JAK3GPR119CNR2PRMT5WDR77 | |
| SCHEMBL23584748 | 0.85 | GPR119 (0.40) | JAK3GPR119CNR2PRMT5WDR77 | |
| SCHEMBL25047907 | 0.85 | GPR119 (0.39) | JAK3GPR119CNR2PRMT5WDR77 | |
| SCHEMBL23584653 | 0.85 | PRMT5 (0.49) | JAK3GPR119CNR2PRMT5WDR77 | |
| SCHEMBL23584786 | 0.79 | PRMT5 (0.47) | GPR119CNR2PRMT5WDR77SRC | |
| SCHEMBL23584762 | 0.79 | CNR2 (0.39) | JAK3GPR119CNR2PRMT5CNR1 | |
| SCHEMBL25048285 | 0.71 | MEN1 (0.41) | JAK3PRMT5WDR77PIK3CACDK2 | |
| SCHEMBL23584773 | 0.71 | PRMT5 (0.51) | JAK3PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |