Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | USP7 | Q93009 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | UBA6 | A0AVT1 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23584748 | 0.94 | GPR119 (0.40) | GPR119PRMT5WDR77CNR2JAK3 | |
| SCHEMBL25048811 | 0.94 | GPR119 (0.40) | GPR119PRMT5WDR77CNR2JAK3 | |
| SCHEMBL25048435 | 0.87 | JAK3 (0.40) | GPR119PRMT5WDR77CNR2JAK3 | |
| SCHEMBL23584762 | 0.85 | CNR2 (0.39) | GPR119PRMT5CNR2JAK3SRC | |
| SCHEMBL25047504 | 0.85 | JAK3 (0.40) | GPR119PRMT5WDR77CNR2JAK3 | |
| SCHEMBL23584763 | 0.85 | PRMT5 (0.40) | GPR119PRMT5WDR77CNR2JAK3 | |
| SCHEMBL23584653 | 0.85 | PRMT5 (0.49) | GPR119PRMT5WDR77CNR2JAK3 | |
| SCHEMBL25047907 | 0.83 | GPR119 (0.39) | GPR119PRMT5WDR77CNR2JAK3 | |
| SCHEMBL23584773 | 0.82 | PRMT5 (0.51) | PRMT5WDR77JAK3 | |
| SCHEMBL25048841 | 0.81 | PRMT5 (0.36) | GPR119PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |