Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 6/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 10/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30941527 | 1.00 | PRMT5 (0.37) | PRMT5CA2METTL3ADORA3 | |
| SCHEMBL30941036 | 0.90 | METTL3 (0.43) | PRMT5CA2METTL3 | |
| SCHEMBL30940869 | 0.90 | METTL3 (0.38) | PRMT5CA2METTL3ADORA3 | |
| SCHEMBL25048824 | 0.90 | METTL3 (0.43) | PRMT5CA2METTL3 | |
| SCHEMBL25048513 | 0.90 | METTL3 (0.38) | PRMT5CA2METTL3ADORA3 | |
| SCHEMBL30941506 | 0.88 | ADK (0.40) | PRMT5CA2METTL3ADORA3 | |
| SCHEMBL25048505 | 0.86 | CA2 (0.40) | PRMT5CA2METTL3ADORA3 | |
| SCHEMBL25048521 | 0.85 | PRMT5 (0.41) | PRMT5CA2METTL3 | |
| SCHEMBL30941198 | 0.85 | PRMT5 (0.41) | PRMT5CA2METTL3 | |
| SCHEMBL25048823 | 0.82 | METTL3 (0.43) | PRMT5CA2METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |