Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.53 |
| ▸ | METTL3 | Q86U44 | 14/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | AHCY | P23526 | 1/20 | 0.41 |
| ▸ | METTL14 | Q9HCE5 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | ABL2 | P42684 | 2/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31617975 | 1.00 | ADK (0.53) | ADKMETTL3MTORRAB9AAHCY | |
| SCHEMBL25046626 | 0.94 | ADK (0.49) | ADKMETTL3MTORRAB9AAHCY | |
| SCHEMBL31617936 | 0.87 | AHCY (0.56) | ADKMETTL3MTORRAB9AAHCY | |
| SCHEMBL25047853 | 0.87 | AHCY (0.56) | ADKMETTL3MTORRAB9AAHCY | |
| SCHEMBL25048732 | 0.79 | ADK (0.42) | ADKMETTL3RIPK2 | |
| SCHEMBL30941042 | 0.78 | ADK (0.55) | ADKMETTL3MTORRAB9AABL1 | |
| SCHEMBL25046789 | 0.78 | ADK (0.55) | ADKMETTL3MTORRAB9AABL1 | |
| SCHEMBL30941267 | 0.76 | ADK (0.54) | ADKMETTL3MTORRAB9AAHCY | |
| SCHEMBL25049361 | 0.76 | ADK (0.54) | ADKMETTL3MTORRAB9AAHCY | |
| SCHEMBL25046627 | 0.74 | ADK (0.45) | ADKABL1EGFRABL2RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |