Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.42 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 6/20 | 0.32 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | SIK1 | P57059 | 1/20 | 0.32 |
| ▸ | RIPK4 | P57078 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | DSTYK | Q6XUX3 | 1/20 | 0.32 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25046626 | 0.85 | ADK (0.49) | ADKMETTL3 | |
| SCHEMBL25048738 | 0.84 | METTL3 (0.46) | ADKMETTL3 | |
| SCHEMBL25048548 | 0.79 | ADK (0.53) | ADKMETTL3RIPK2 | |
| SCHEMBL31617975 | 0.79 | ADK (0.53) | ADKMETTL3RIPK2 | |
| SCHEMBL25046627 | 0.78 | ADK (0.45) | ADKRIPK2PIKFYVEPDGFRBKIT | |
| SCHEMBL25047636 | 0.77 | PRMT5 (0.45) | — | |
| SCHEMBL25047443 | 0.77 | ADK (0.40) | ADKMETTL3 | |
| SCHEMBL25048721 | 0.72 | PRMT5 (0.35) | — | |
| SCHEMBL25048597 | 0.70 | ADK (0.35) | ADKFGFR4 | |
| SCHEMBL30941245 | 0.70 | ADK (0.35) | ADKFGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |