Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC3R | P41968 | 11/20 | 0.47 |
| ▸ | MC4R | P32245 | 9/20 | 0.47 |
| ▸ | MC5R | P33032 | 13/20 | 0.43 |
| ▸ | MC1R | Q01726 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30941017 | 0.87 | MC3R (0.50) | MC3RMC4RMC5RMC1RHDAC3 | |
| SCHEMBL3312799 | 0.87 | MC3R (0.50) | MC3RMC4RMC5RMC1RHDAC3 | |
| SCHEMBL13783897 | 0.85 | CYP1A2 (0.54) | MC3RMC4RMC5RMC1RHDAC3 | |
| SCHEMBL13783902 | 0.82 | HDAC1 (0.58) | MC3RMC4RHDAC3HDAC1HDAC2 | |
| SCHEMBL25047687 | 0.81 | MC4R (0.44) | MC3RMC4RMC5RMC1RHDAC3 | |
| SCHEMBL13783994 | 0.81 | HDAC1 (0.65) | HDAC3HDAC1HDAC2NCOR2HDAC8 | |
| SCHEMBL26654244 | 0.80 | MC4R (0.49) | MC3RMC4RMC5RMC1RHDAC3 | |
| SCHEMBL26654243 | 0.80 | MC4R (0.49) | MC3RMC4RMC5RMC1RHDAC3 | |
| SCHEMBL31617921 | 0.78 | SIGMAR1 (0.41) | MC3RMC4RMC5RHDAC1SIGMAR1 | |
| SCHEMBL25046547 | 0.78 | SIGMAR1 (0.41) | MC3RMC4RMC5RHDAC1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |