Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 8/20 | 0.49 |
| ▸ | MC3R | P41968 | 8/20 | 0.49 |
| ▸ | MC5R | P33032 | 8/20 | 0.49 |
| ▸ | MC1R | Q01726 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26654244 | 1.00 | MC4R (0.49) | MC4RMC3RMC5RMC1RF2 | |
| SCHEMBL30627388 | 0.90 | MC4R (0.46) | MC4RMC3RMC5RMC1RF2 | |
| SCHEMBL13783897 | 0.83 | CYP1A2 (0.54) | MC4RMC3RMC5RMC1RHDAC3 | |
| SCHEMBL30941017 | 0.82 | MC3R (0.50) | MC4RMC3RMC5RMC1RF2 | |
| SCHEMBL3312799 | 0.82 | MC3R (0.50) | MC4RMC3RMC5RMC1RF2 | |
| SCHEMBL26654294 | 0.81 | TGM2 (0.54) | F2HDAC1HDAC2CTSBCTSS | |
| SCHEMBL26654189 | 0.81 | CTSB (0.42) | MC4RMC3RMC5RHDAC3HDAC1 | |
| SCHEMBL26654354 | 0.81 | CTSB (0.42) | MC4RMC3RMC5RHDAC3HDAC1 | |
| SCHEMBL26654193 | 0.81 | CTSB (0.42) | MC4RMC3RMC5RHDAC3HDAC1 | |
| SCHEMBL26654291 | 0.81 | TGM2 (0.54) | F2HDAC1HDAC2CTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023223057-A1 | MACROCYCLIC COMPOUNDS AND USES THEREOF | CYPRALIS LIMITED (GB) | 2023-11-23 | — | — | WO | disclosed |