Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 11/20 | 0.34 |
| ▸ | CNR1 | P21554 | 10/20 | 0.34 |
| ▸ | INSR | P06213 | 3/20 | 0.33 |
| ▸ | IGF1R | P08069 | 3/20 | 0.33 |
| ▸ | LCK | P06239 | 3/20 | 0.32 |
| ▸ | SRC | P12931 | 3/20 | 0.32 |
| ▸ | BTK | Q06187 | 3/20 | 0.32 |
| ▸ | LYN | P07948 | 2/20 | 0.32 |
| ▸ | KIT | P10721 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.32 |
| ▸ | FLT1 | P17948 | 2/20 | 0.32 |
| ▸ | FLT4 | P35916 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | FLT3 | P36888 | 2/20 | 0.32 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.32 |
| ▸ | TEK | Q02763 | 2/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25049346 | 0.89 | KCNH2 (0.36) | KCNH2CNR1INSRIGF1RLCK | |
| SCHEMBL25048943 | 0.87 | C1S (0.35) | KCNH2INSRIGF1RLCKSRC | |
| SCHEMBL30941197 | 0.86 | CNR1 (0.36) | KCNH2CNR1CYP1A1CYP2C8CYP2D6 | |
| SCHEMBL31618049 | 0.86 | CNR1 (0.36) | KCNH2CNR1CYP1A1CYP2C8CYP2D6 | |
| SCHEMBL25047576 | 0.86 | CNR1 (0.36) | KCNH2CNR1CYP1A1CYP2C8CYP2D6 | |
| SCHEMBL25047574 | 0.86 | CNR1 (0.36) | KCNH2CNR1CYP1A1CYP2C8CYP2D6 | |
| SCHEMBL25048047 | 0.86 | C1S (0.33) | KCNH2LCKSRCBTKEGFR | |
| SCHEMBL25047567 | 0.85 | C1S (0.36) | KCNH2INSRIGF1RLCKSRC | |
| SCHEMBL25048024 | 0.83 | SRC (0.35) | IGF1RLCKSRCKDRTEK | |
| SCHEMBL25047579 | 0.82 | EGFR (0.36) | KCNH2IGF1RLCKSRCFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |