Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 3/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ABL2 | P42684 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.35 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048705 | 0.90 | CCR8 (0.40) | CCR8ABL1EGFRABL2CHKA | |
| SCHEMBL25047841 | 0.86 | MEN1 (0.37) | CCR8PRMT5KDM4EFDFT1FFAR1 | |
| SCHEMBL25048298 | 0.85 | PRMT5 (0.42) | PRMT5 | |
| SCHEMBL25048777 | 0.81 | PRMT5 (0.41) | PRMT5FDFT1 | |
| SCHEMBL25049350 | 0.79 | IGF1R (0.38) | CCR8PRMT5ABL1EGFRABL2 | |
| SCHEMBL31618015 | 0.77 | PRMT5 (0.44) | PRMT5 | |
| SCHEMBL25049348 | 0.75 | IGF1R (0.37) | CCR8PRMT5FDFT1 | |
| SCHEMBL25048261 | 0.75 | IGF1R (0.36) | PRMT5ABL1EGFRABL2FFAR1 | |
| SCHEMBL25047840 | 0.75 | PRMT5 (0.40) | PRMT5FDFT1 | |
| SCHEMBL25048701 | 0.75 | PRMT5 (0.40) | PRMT5KDM4EFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |