Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 3/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 4/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31618030 | 0.89 | CA2 (0.34) | METTL3PRMT5WDR77 | |
| SCHEMBL25048380 | 0.86 | ACKR3 (0.31) | KDM1ASRC | |
| SCHEMBL25048278 | 0.83 | METTL3 (0.39) | METTL3PRMT5WDR77 | |
| SCHEMBL25048782 | 0.83 | IGF1R (0.32) | METTL3PRMT5WDR77IGF1RSRC | |
| SCHEMBL31617889 | 0.81 | METTL3 (0.37) | METTL3PRMT5WDR77 | |
| SCHEMBL25048791 | 0.79 | IGF1R (0.33) | METTL3PRMT5WDR77IGF1R | |
| SCHEMBL25048184 | 0.78 | KDM1A (0.31) | KDM1ASRC | |
| SCHEMBL25048309 | 0.78 | PRMT5 (0.31) | METTL3PRMT5WDR77 | |
| SCHEMBL31617928 | 0.76 | NT5E (0.32) | METTL3PRMT5WDR77 | |
| SCHEMBL31617898 | 0.76 | CA2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |