Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.31 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25048099 | 0.91 | METTL3 (0.36) | PRMT5METTL3WDR77 | |
| SCHEMBL25049234 | 0.85 | — | — | |
| SCHEMBL25048360 | 0.82 | RIPK2 (0.30) | — | |
| SCHEMBL25049371 | 0.81 | CA2 (0.34) | PRMT5METTL3WDR77 | |
| SCHEMBL25048311 | 0.79 | — | — | |
| SCHEMBL25048791 | 0.79 | IGF1R (0.33) | PRMT5METTL3WDR77 | |
| SCHEMBL25047679 | 0.78 | AXL (0.35) | — | |
| SCHEMBL25049202 | 0.78 | METTL3 (0.32) | PRMT5METTL3WDR77 | |
| SCHEMBL25046747 | 0.74 | C1S (0.33) | — | |
| SCHEMBL25048547 | 0.74 | CA2 (0.39) | PRMT5METTL3WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |