Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 4/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | DRD4 | P21917 | 3/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | DRD5 | P21918 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PRCP | P42785 | 1/20 | 0.42 |
| ▸ | EBP | Q15125 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340318 | 0.90 | BCHE (0.47) | SIGMAR1 | |
| SCHEMBL25531092 | 0.89 | GBA1 (0.41) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL26632276 | 0.87 | DRD2 (0.49) | DRD3DRD2DRD4DRD1DRD5 | |
| Hydrochloric Acid SCHEMBL30213326 | 0.85 | DRD2 (0.47) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL4377471 | 0.85 | HSD11B1 (0.39) | DRD3DRD2 | |
| SCHEMBL28250446 | 0.85 | HSD11B1 (0.39) | DRD3DRD2 | |
| SCHEMBL5066037 | 0.85 | DRD3 (0.47) | DRD3DRD2DRD4DRD1DRD5 | |
| Hydrochloric Acid SCHEMBL30330348 | 0.82 | CYP1A2 (0.48) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL10646171 | 0.82 | LSS (0.48) | DRD3DRD2DRD4DRD1DRD5 | |
| SCHEMBL7655261 | 0.82 | ACHE (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018810-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2023-02-16 | — | — | WO | disclosed |