SCHEMBL25049883

SCHEMBL25049883

c1ccc(-c2ccc(-c3ccccc3-c3nc(-c4cccc5c4oc4ccccc45)nc(-c4cccc5sc6ccccc6c45)n3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.41
BRDT Q58F21 1/20 0.36
PRKDC P78527 4/20 0.34
PIK3CD O00329 2/20 0.34
PIK3CB P42338 2/20 0.34
GGPS1 O95749 1/20 0.34
MAPT P10636 4/20 0.33
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
POLB P06746 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
CDC14B O60729 1/20 0.32
CDC14A Q9UNH5 1/20 0.32
MEN1 O00255 1/20 0.32
CSF1R P07333 1/20 0.32
PDGFRB P09619 1/20 0.32
KIT P10721 1/20 0.32
FLT3 P36888 1/20 0.32
KMT2A Q03164 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25050118 0.98 ALOX5 (0.40) ALOX5BRDTPRKDCPIK3CDPIK3CB
SCHEMBL25950880 0.97 ALOX5 (0.39) ALOX5BRDTPRKDCPIK3CDPIK3CB
SCHEMBL26080470 0.95 ALOX5 (0.41) ALOX5BRDTPRKDCPIK3CDPIK3CB
SCHEMBL22085639 0.94 ALOX5 (0.40) ALOX5BRDTPRKDCPIK3CDPIK3CB
SCHEMBL25645969 0.93 ALOX5 (0.41) ALOX5BRDTPRKDCPIK3CDPIK3CB
SCHEMBL21425045 0.93 ALOX5 (0.43) ALOX5BRDTPRKDCPIK3CDPIK3CB
SCHEMBL26080454 0.92 ALOX5 (0.41) ALOX5BRDTPRKDCPIK3CDPIK3CB
SCHEMBL26080461 0.92 ALOX5 (0.41) ALOX5BRDTPRKDCPIK3CDPIK3CB
SCHEMBL25050225 0.91 ALOX5 (0.40) ALOX5BRDTPRKDCPIK3CDPIK3CB
SCHEMBL26080463 0.91 ALOX5 (0.39) ALOX5BRDTPRKDCPIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230312538-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2023-10-05 US disclosed
US-20230312538-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2023-10-05 US disclosed
EP-4212526-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LT Materials Co., Ltd. (KR) 2023-07-19 EP disclosed
US-20230047894-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230047894-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME AOC2, OR10J3, AOC3 ALOX5 3242/4885BRDT 2172/4885PRKDC 4824/4885
US-20230312538-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, CYP1A1, CYP1B1 ALOX5 579/4885BRDT 2774/4885PRKDC 4577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.