SCHEMBL3206960

SCHEMBL3206960

CC(=O)OC1CCN(Cc2ccccc2)C1

nearest known ligand 0.67

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BCHE P06276 5/20 0.60
MAOB P27338 2/20 0.58
ACHE P22303 2/20 0.50
SCN4A P35499 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9685669 1.00 BCHE (0.60) BCHEMAOBACHESCN4A
SCHEMBL2893650 1.00 BCHE (0.60) BCHEMAOBACHESCN4A
SCHEMBL19038337 0.92 BCHE (0.72) BCHEMAOBACHE
SCHEMBL4135213 0.91 BCHE (0.67) BCHEACHE
Hydrochloric Acid SCHEMBL9380707 0.90 BCHE (0.65) BCHEACHE
SCHEMBL11478274 0.89 BCHE (0.54) BCHEMAOB
SCHEMBL250507 0.88 BCHE (0.61) BCHEMAOB
SCHEMBL7301577 0.87 BCHE (0.57) BCHEMAOBSCN4A
SCHEMBL8915069 0.87 BCHE (0.57) BCHEMAOBSCN4A
SCHEMBL27315592 0.86 BCHE (0.61) BCHEMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1113365-A None JP disclosed
JP-5227991-A None JP disclosed
CN-111808007-A Preparation method of chiral 3-substituted pyrrolidine derivative 青岛贞开生物医药技术有限公司 2020-10-23 CN disclosed
CN-108884068-A 1- cyano-pyrolidin derivative as DUB inhibitor 特殊治疗有限公司 2018-11-23 CN disclosed
US-8940782-B2 Composition for repelling and deterring vermin NOVARTIS AG (CH) 2015-01-27 US disclosed
US-20130143924-A1 COMPOSITION FOR REPELLING AND DETERRING VERMIN ELANCO TIERGESUNDHEIT AG (CH) 2013-06-06 US disclosed
US-8338490-B2 Composition for repelling and deterring vermin NOVARTIS AG (CH) 2012-12-25 US disclosed
EP-2094079-B1 COMPOSITION FOR REPELLING AND DETERRING VERMIN NOVARTIS AG (CH) 2012-11-14 EP disclosed
WO-2010049678-A2 TREATMENT OF ENERGY UTILIZATION DISEASES SUMMIT CORPORATION PLC (GB) 2010-05-06 WO disclosed
US-20100063090-A1 Composition for Repelling and Deterring Vermin NOVARTIS AG (CH) 2010-03-11 US disclosed
WO-2010015815-A2 COMPOUNDS FOR THE TREATMENT OF FLAVIVIRAL INFECTIONS SUMMIT CORPORATION PLC (GB) 2010-02-11 WO disclosed
EP-2094079-A1 COMPOSITION FOR REPELLING AND DETERRING VERMIN Novartis Ag (CH) 2009-09-02 EP disclosed
WO-2008062006-A1 COMPOSITION FOR REPELLING AND DETERRING VERMIN NOVARTIS AG (CH) 2008-05-29 WO disclosed
EP-1114027-B1 THE PREPARATION OF N-SUBSTITUTED-HYDROXYCYCLOALKYLAMINE DERIVATIVES SAMSUNG FINE CHEMICALS CO LTD (KR) 2003-06-04 EP disclosed
US-6566525-B1 Reacting a 1,2-dihydroxalkyl alcohol with a thionyl halide to produce an intermediate 1,2-cyclosulfinylalkyl halide, and then cyclizing that intermediate with an amine compound SAMSUNG FINE CHEMICALS CO., LTD. (KR) 2003-05-20 US disclosed
EP-1114027-A1 THE PREPARATION OF N-SUBSTITUTED-HYDROXYCYCLOALKYLAMINE DERIVATIVES Samsung Fine Chemicals Co., Ltd. (KR) 2001-07-11 EP disclosed
WO-2000015610-A1 THE PREPARATION OF N-SUBSTITUTED-HYDROXYCYCLOALKYLAMINE DERIVATIVES SAMSUNG FINE CHEMICALS CO., LTD. (KR) 2000-03-23 WO disclosed
JP-H05227991-A PRODUCTION OF OPTICALLY ACTIVE 3-PYRROLIDINOL DERIVATIVE KYOWA HAKKO KOGYO CO LTD 1993-09-07 JP disclosed
JP-H01113365-A NOVEL PYRROLIDINE DERIVATIVE AND PRODUCTION THEREOF KANEGAFUCHI CHEM IND CO LTD 1989-05-02 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100063090-A1 Composition for Repelling and Deterring Vermin AAAS, SERPINC1, FABP1 BCHE 40/4885MAOB 990/4885ACHE 27/4885
US-20130143924-A1 COMPOSITION FOR REPELLING AND DETERRING VERMIN ACHE, PNMT, AAAS BCHE 5/4885MAOB 517/4885ACHE 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.