Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11728287 | 1.00 | CYP3A4 (0.48) | CYP3A4TDP1CES2CES1ESR1 | |
| SCHEMBL9862135 | 0.98 | CYP3A4 (0.50) | CYP3A4TDP1CES2CES1ESR1 | |
| SCHEMBL27372739 | 0.89 | CYP3A4 (0.60) | CYP3A4TDP1CES2CES1ESR1 | |
| Dodecane SCHEMBL27373256 | 0.89 | CYP3A4 (0.60) | CYP3A4TDP1CES2CES1ESR1 | |
| Heptane SCHEMBL27734164 | 0.89 | CYP3A4 (0.60) | CYP3A4TDP1CES2CES1ESR1 | |
| Pentadecane SCHEMBL27707032 | 0.89 | CYP3A4 (0.60) | CYP3A4TDP1CES2CES1ESR1 | |
| Tridecane SCHEMBL27393394 | 0.89 | CYP3A4 (0.60) | CYP3A4TDP1CES2CES1ESR1 | |
| Tetradecane SCHEMBL27451965 | 0.89 | CYP3A4 (0.60) | CYP3A4TDP1CES2CES1ESR1 | |
| Heptane SCHEMBL28244261 | 0.89 | CYP3A4 (0.60) | CYP3A4TDP1CES2CES1ESR1 | |
| Undecane SCHEMBL28327061 | 0.89 | CYP3A4 (0.60) | CYP3A4TDP1CES2CES1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9308214-B2 | Method for moderately increasing the proton conductivity of biological membranes with the aid of mitochondria-targeted delocalized cations | MITOTECH S.A. (LU) | 2016-04-12 | — | — | US | disclosed |
| US-20110245207-A1 | METHOD FOR MODERATELY INCREASING THE PROTON CONDUCTIVITY OF BIOLOGICAL MEMBRANES WITH THE AID OF MITOCHONDRIA-TARGETED DELOCALIZED CATIONS | MITOTECH SA (LU) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245207-A1 | METHOD FOR MODERATELY INCREASING THE PROTON CONDUCTIVITY OF BIOLOGICAL MEMBRANES WITH THE AID OF MITOCHONDRIA-TARGETED DELOCALIZED CATIONS | MCU, AGK, TFAM | CYP3A4 1985/4885TDP1 2699/4885CES2 3181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.