Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | RXRG | P48443 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | BAD | Q92934 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23576546 | 0.97 | RXRA (0.33) | SMN1; SMN2NOS3NOS1NOS2RXRA | |
| SCHEMBL31401385 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2NOS3NOS1NOS2RXRA | |
| SCHEMBL903596 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2NOS3NOS1NOS2RXRA | |
| SCHEMBL25053529 | 0.71 | NOS3 (0.36) | SMN1; SMN2NOS3NOS1NOS2STAT3 | |
| SCHEMBL25238832 | 0.70 | SMN1; SMN2 (0.38) | SMN1; SMN2RXRARXRBPPARGRXRG | |
| SCHEMBL28850910 | 0.69 | STAT3 (0.35) | SMN1; SMN2NOS3NOS1NOS2RXRA | |
| SCHEMBL30044128 | 0.69 | STAT3 (0.35) | SMN1; SMN2NOS3NOS1NOS2RXRA | |
| SCHEMBL23592236 | 0.69 | STAT3 (0.47) | SMN1; SMN2NOS3NOS1NOS2NQO1 | |
| SCHEMBL23593806 | 0.68 | SMN1; SMN2 (0.36) | SMN1; SMN2NOS3NOS1NOS2RXRA | |
| SCHEMBL30044393 | 0.68 | SMN1; SMN2 (0.36) | SMN1; SMN2NOS3NOS1NOS2RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230050670-A1 | TETRAHYDROBENZO-QUINOLINE SULFONAMIDE DERIVATIVES USEFUL AS IGE MODULATORS | UCB Biopharma SRL (BE) | 2023-02-16 | — | — | US | disclosed |
| CN-114845776-A | Tetrahydrobenzo-quinoline sulfonamide derivatives useful as IGE modulators | UCB生物制药有限责任公司 | 2022-08-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230050670-A1 | TETRAHYDROBENZO-QUINOLINE SULFONAMIDE DERIVATIVES USEFUL AS IGE MODULATORS | FCER2, FCGR1A, FCGR2A | SMN1; SMN2 4828/4885NOS3 593/4885NOS1 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.