Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4136645 | 0.77 | SLC6A4 (0.43) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL25053533 | 0.76 | USP2 (0.31) | SLC6A2SLC6A4SLC6A3USP2ALDH1A1 | |
| SCHEMBL29082372 | 0.75 | SIGMAR1 (0.45) | CHRNB2CHRNA4PRCPMEN1KMT2A | |
| SCHEMBL24365456 | 0.75 | SIGMAR1 (0.45) | CHRNB2CHRNA4PRCPMEN1KMT2A | |
| SCHEMBL3245656 | 0.74 | HTT (0.36) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL14855593 | 0.72 | TRPM8 (0.41) | MEN1KMT2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL27868917 | 0.72 | SLC18A3 (0.36) | KDM1ACHRNB2CHRNA4PRCPMEN1 | |
| Hydrochloric Acid SCHEMBL30142162 | 0.71 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3KDM1AMEN1 | |
| Hydrochloric Acid SCHEMBL27077276 | 0.71 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3KDM1AMEN1 | |
| SCHEMBL14855772 | 0.71 | TRPM8 (0.44) | MEN1KMT2AUSP2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022200523-A9 | PHARMACEUTICAL COMPOUNDS AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 19 (USP19) | ALMAC DISCOVERY LIMITED (GB) | 2023-02-16 | — | — | WO | disclosed |