SCHEMBL25053709

SCHEMBL25053709

Cc1cccc(/C=C/c2ccc(N(c3ccc(/C=C/c4ccc(/C=C/c5ccc(N(c6ccc(/C=C/c7cccc(C)c7)cc6)c6ccc(C)cc6C)cc5)cc4)cc3)c3ccc(C)cc3C)cc2)c1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RELA Q04206 2/20 0.50
PTGS1 P23219 3/20 0.47
PTGS2 P35354 3/20 0.47
ALOX5 P09917 2/20 0.47
NFE2L2 Q16236 4/20 0.45
APP P05067 4/20 0.42
FBP1 P09467 1/20 0.40
TP53 P04637 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
NPC1 O15118 1/20 0.39
CASP3 P42574 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
NR1H3 Q13133 1/20 0.38
MAOB P27338 1/20 0.37
INSR P06213 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14727223 0.96 RELA (0.47) RELAPTGS1PTGS2ALOX5NFE2L2
SCHEMBL15496738 0.94 RELA (0.46) RELAPTGS1PTGS2ALOX5NFE2L2
SCHEMBL4400841 0.94 NFE2L2 (0.49) RELAPTGS1PTGS2ALOX5NFE2L2
SCHEMBL18353269 0.91 RELA (0.44) RELAPTGS1PTGS2ALOX5NFE2L2
SCHEMBL14727230 0.91 RELA (0.49) RELAPTGS1PTGS2ALOX5NFE2L2
SCHEMBL18418091 0.91 RELA (0.49) RELAPTGS1PTGS2ALOX5NFE2L2
SCHEMBL15496795 0.90 RELA (0.58) RELANFE2L2APP
SCHEMBL12680417 0.89 RELA (0.47) RELAPTGS1PTGS2ALOX5NFE2L2
SCHEMBL17325961 0.89 RELA (0.40) RELAPTGS1PTGS2ALOX5NFE2L2
SCHEMBL15496780 0.89 RELA (0.40) RELAPTGS1PTGS2ALOX5NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11586119-B2 Electrophotographic photoconductor, method of manufacturing the same, and electrophotographic device FUJI ELECTRIC CO., LTD. (JP) 2023-02-21 US disclosed