SCHEMBL4400841

SCHEMBL4400841

Cc1ccc(N(c2ccc(C=Cc3cccc(C=Cc4ccc(N(c5ccc(C)cc5)c5ccc(C)cc5C)cc4)c3)cc2)c2ccc(C)cc2C)cc1

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 6/20 0.49
APP P05067 7/20 0.43
RELA Q04206 2/20 0.43
ALOX5 P09917 2/20 0.41
PTGS1 P23219 2/20 0.41
PTGS2 P35354 2/20 0.41
INSR P06213 1/20 0.36
KDM4E B2RXH2 1/20 0.36
HPGD P15428 1/20 0.36
NR1H3 Q13133 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22502950 0.94 NFE2L2 (0.43) NFE2L2APPRELAALOX5PTGS1
SCHEMBL18353269 0.94 RELA (0.44) NFE2L2APPRELAALOX5PTGS1
SCHEMBL25053709 0.94 RELA (0.50) NFE2L2APPRELAALOX5PTGS1
SCHEMBL12680417 0.92 RELA (0.47) NFE2L2RELAALOX5PTGS1PTGS2
SCHEMBL16489740 0.92 PTGS1 (0.46) NFE2L2APPRELAALOX5PTGS1
SCHEMBL442631 0.92 PTGS1 (0.46) NFE2L2APPRELAALOX5PTGS1
SCHEMBL30394669 0.92 PTGS1 (0.46) NFE2L2APPRELAALOX5PTGS1
SCHEMBL12056063 0.92 PTGS1 (0.46) NFE2L2APPRELAALOX5PTGS1
SCHEMBL14727232 0.92 PTGS1 (0.46) NFE2L2APPRELAALOX5PTGS1
SCHEMBL140662 0.92 PTGS1 (0.46) NFE2L2APPRELAALOX5PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
EP-2138899-B1 Electrophotographic photoreceptor, image forming apparatus using the electrophotographic photoreceptor, and method of producing electrophotographic photoreceptor RICOH CO LTD (JP) 2013-02-27 EP disclosed
US-20130022902-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD AND APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-01-24 US disclosed
US-20130022902-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD AND APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-01-24 US disclosed
US-20120321348-A1 IMAGE BEARING DRUM, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2012-12-20 US disclosed
US-20120321348-A1 IMAGE BEARING DRUM, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2012-12-20 US disclosed
US-8273513-B2 Image forming apparatus, process cartridge, and image bearing member RICOH COMPANY, LIMITED (JP) 2012-09-25 US disclosed
US-8273513-B2 Image forming apparatus, process cartridge, and image bearing member RICOH COMPANY, LIMITED (JP) 2012-09-25 US disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 US disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 US disclosed
US-20090180788-A1 Image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2009-07-16 US disclosed
US-20090180788-A1 Image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2009-07-16 US disclosed
US-20090035017-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND METHOD FOR PRODUCING THE SAME, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2009-02-05 US disclosed
US-20090035017-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND METHOD FOR PRODUCING THE SAME, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2009-02-05 US disclosed
US-20080292981-A1 IMAGE BEARING MEMBER AND IMAGE FORMING APPARATUS USING THE SAME RICOH COMPANY LIMITED (JP) 2008-11-27 US disclosed
US-20080292981-A1 IMAGE BEARING MEMBER AND IMAGE FORMING APPARATUS USING THE SAME RICOH COMPANY LIMITED (JP) 2008-11-27 US disclosed
US-20080227007-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-09-18 US disclosed
US-20080227007-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2008-09-18 US disclosed