Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.41 |
| ▸ | QRFPR | Q96P65 | 5/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | NMT2 | O60551 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | NPY4R | P50391 | 3/20 | 0.34 |
| ▸ | NPY1R | P25929 | 2/20 | 0.34 |
| ▸ | NPY2R | P49146 | 2/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26426329 | 0.86 | QRFPR (0.42) | NOD1SIRT5QRFPRALBTLR2 | |
| SCHEMBL16283730 | 0.81 | NOD1 (0.50) | NOD1SIRT5ALBTLR2SIRT6 | |
| SCHEMBL16285430 | 0.81 | SIRT5 (0.58) | NOD1SIRT5ALBTLR2SIRT6 | |
| SCHEMBL23618500 | 0.80 | SIRT5 (0.50) | SIRT5QRFPRALBTLR2SIRT6 | |
| SCHEMBL22674899 | 0.78 | FURIN (0.42) | NOD1QRFPRTLR2SIRT6SIRT1 | |
| SCHEMBL16283873 | 0.77 | NOD1 (0.47) | NOD1SIRT5ALBTLR2SIRT6 | |
| SCHEMBL31686179 | 0.77 | NOD1 (0.55) | NOD1TLR2SIRT6SIRT1NMT2 | |
| SCHEMBL20653679 | 0.77 | NOD1 (0.55) | NOD1TLR2SIRT6SIRT1NMT2 | |
| SCHEMBL30435754 | 0.77 | NOD1 (0.46) | NOD1TLR2SIRT6SIRT1NMT2 | |
| SCHEMBL13120896 | 0.77 | ALB (0.49) | NOD1SIRT5QRFPRALBTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11583569-B2 | PSMA-targeting amanitin conjugates | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2023-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11583569-B2 | PSMA-targeting amanitin conjugates | FOLH1, ANPEP, PSMA6 | NOD1 3723/4885SIRT5 2082/4885QRFPR 241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.