Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QRFPR | Q96P65 | 7/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22133062 | 0.89 | HPGDS (0.42) | QRFPRTLR2SIRT6SIRT1ROCK2 | |
| SCHEMBL15302247 | 0.89 | HPGDS (0.42) | QRFPRTLR2SIRT6SIRT1ROCK2 | |
| SCHEMBL2159831 | 0.89 | HPGDS (0.42) | QRFPRTLR2SIRT6SIRT1ROCK2 | |
| SCHEMBL1352085 | 0.88 | HPGDS (0.43) | QRFPRTLR2SIRT6SIRT1ROCK2 | |
| SCHEMBL13120896 | 0.87 | ALB (0.49) | QRFPRALBSIRT5TLR2SIRT6 | |
| SCHEMBL25055301 | 0.86 | NOD1 (0.47) | QRFPRALBSIRT5TLR2SIRT6 | |
| SCHEMBL10033607 | 0.86 | ALB (0.45) | ALBSIRT5TLR2SIRT6SIRT1 | |
| SCHEMBL6188760 | 0.85 | QRFPR (0.43) | QRFPR | |
| SCHEMBL17985757 | 0.85 | QRFPR (0.43) | QRFPR | |
| SCHEMBL13165492 | 0.85 | MEN1 (0.52) | QRFPRALBSIRT5TLR2SIRT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069502-A2 | PEPTIDE CONJUGATES AND THERAPEUTIC AGENTS HAVING IMPROVED PHARMACOLOGICAL AND PHARMACOKINETIC PROPERTIES | RESOLUTE BIO, INC. (US) | 2023-04-27 | — | — | WO | disclosed |