Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD74 | P04233 | 3/20 | 0.73 |
| ▸ | MIF | P14174 | 3/20 | 0.73 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.63 |
| ▸ | GSK3B | P49841 | 1/20 | 0.63 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.63 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.59 |
| ▸ | TEK | Q02763 | 5/20 | 0.58 |
| ▸ | KDR | P35968 | 5/20 | 0.58 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29275463 | 0.89 | CYP19A1 (0.72) | CD74MIFROCK2GSK3BAURKB | |
| SCHEMBL30185437 | 0.89 | CYP19A1 (0.72) | CD74MIFROCK2GSK3BAURKB | |
| SCHEMBL27983562 | 0.88 | ESRRG (0.63) | CD74MIFROCK2GSK3BAURKB | |
| SCHEMBL12419414 | 0.87 | ROCK2 (0.58) | CD74MIFROCK2GSK3BAURKB | |
| SCHEMBL25055361 | 0.84 | CD74 (1.00) | CD74MIFHSP90AA1HSP90AB1NPC1 | |
| SCHEMBL29352717 | 0.81 | CYP19A1 (0.72) | ROCK2GSK3BAURKBTEKKDR | |
| SCHEMBL16050564 | 0.81 | CYP19A1 (0.72) | ROCK2GSK3BAURKBTEKKDR | |
| SCHEMBL12535881 | 0.79 | NPC1 (0.88) | GSK3BTEKKDREPHB4NPC1 | |
| SCHEMBL3666031 | 0.78 | ROCK2 (1.00) | ROCK2GSK3BAURKBTEKKDR | |
| SCHEMBL28331496 | 0.77 | NPC1 (0.76) | GSK3BTEKKDREPHB4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11584717-B2 | MIF modulators | YALE UNIVERSITY (US) | 2023-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11584717-B2 | MIF modulators | MIF, HMGB2, HMGB3 | CD74 15/4885MIF 1/4885ROCK2 1403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.