SCHEMBL25058

SCHEMBL25058

COCCC(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16167546 0.97
Hydrochloric Acid SCHEMBL3856798 0.97
Hydrochloric Acid SCHEMBL3240952 0.97
Bromide SCHEMBL5483265 0.97
Acetamide SCHEMBL8500646 0.95 ALOX15 (0.42)
Methylene Chloride SCHEMBL28156284 0.92 ALDH1A1 (0.38)
SCHEMBL228309 0.86
SCHEMBL24801740 0.85 CA2 (0.39)
SCHEMBL19401854 0.85 CA2 (0.39)
SCHEMBL13984666 0.85 CA2 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1407 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024120442-A1 PAK4 PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS CONVERGEN (SUZHOU) PHARMACEUTICAL CO., LTD. (CN) 2024-06-13 WO claimed
CN-117980303-A Novel compounds and their use in the treatment of bacterial infections 豪夫迈·罗氏有限公司 2024-05-03 CN claimed
US-11932646-B2 Small molecule myristate inhibitors of Bcr-abl and methods of use THE SCRIPPS RESEARCH INSTITUTE (US) 2024-03-19 US claimed
EP-4188928-A1 SUBSTITUTED 1 H-PYRROLO[3,2-B]PYRIDIN COMPOUNDS AND METHODS OF USE THEREOF Bayer Aktiengesellschaft (DE) 2023-06-07 EP claimed
CN-115925693-A Selective inhibitors of JAK1 阿斯利康(瑞典)有限公司 2023-04-07 CN claimed
CN-115715195-A Use of partial dopamine D3 agonists for the treatment of central nervous system disorders 生物计划制药公司 2023-02-24 CN claimed
CN-110461830-B Selective inhibitors of JAK1 阿斯利康(瑞典)有限公司 2022-11-01 CN claimed
US-20220135573-A1 SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE DANA-FARBER CANCER INSTITUTE, INC. (US) 2022-05-05 US claimed
EP-3536687-B1 SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE DANA FARBER CANCER INST INC (US) 2021-07-14 EP claimed
EP-3536687-A1 SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE Dana Farber Cancer Institute, Inc. (US) 2019-09-11 EP claimed
EP-0988301-A1 IMIDAZOLYL-CYCLIC ACETALS RHONE-POULENC RORER LIMITED (GB) 2000-03-29 EP claimed
US-5919756-A CHLORORIENTICIN A ANTIBIOTIC ELI LILLY AND COMPANY (US) 1999-07-06 US claimed
EP-0853688-B1 ELECTROLYTIC PLATE STACK CELL BASF AG (DE) 1999-06-09 EP claimed
WO-1998056788-A1 IMIDAZOLYL-CYCLIC ACETALS RHONE-POULENC RORER LIMITED (GB) 1998-12-17 WO claimed
US-5472822-A Imagewise exposing photosensitive material comprising silver halide emulsion layer and physical development nucleus layer on support, developing with diffusion transfer processing solution containing mesoionic compound, neutralizing FUJI PHOTO FILM CO., LTD. (JP) 1995-12-05 US claimed
WO-1994024095-A1 IMMUNOSUPPRESSIVE AGENTS ABBOTT LABORATORIES (US) 1994-10-27 WO claimed
US-5075429-A Colorfastness SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1991-12-24 US claimed
US-4281121-A 1,3,4-Thiadiazole-2-carboxylic acid derivatives, process for making the same and fungicidal and nematocidal compositions containing same SCHERING AKTIENGESELLSCHAFT (DE) 1981-07-28 US claimed
US-4046757-A 2-Optionally substituted alkyl-and phenylsulfonylphenyl-azo-phenyl dyes and a process for their synthesis SANDOZ LTD. (CH) 1977-09-06 US claimed
US-3931268-A Methylhydrazinomethyl-substituted benzoic acid amides HOFFMANN-LA ROCHE INC. (US) 1976-01-06 US claimed