Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | YWHAG | P61981 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | TYR | P14679 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25058875 | 0.83 | EGFR (0.42) | EGFRLCKMEN1KMT2AHSD17B10 | |
| SCHEMBL25058843 | 0.79 | MAPT (0.46) | MEN1KMT2AMAPTALDH1A1RECQL | |
| SCHEMBL23209610 | 0.79 | KMT2A (0.36) | EGFRMEN1KMT2APOLBBRCA1 | |
| SCHEMBL25058840 | 0.77 | IDO1 (0.45) | EGFRLCKMEN1KMT2APOLB | |
| SCHEMBL25058881 | 0.74 | NR3C1 (0.41) | MAOBMAPTALDH1A1RAB9ACYP3A4 | |
| SCHEMBL25058845 | 0.72 | MAPT (0.41) | KMT2APOLBMAOBMAPTALDH1A1 | |
| SCHEMBL25058856 | 0.70 | ALDH1A1 (0.39) | EGFRMEN1KMT2ABRCA1HSD17B10 | |
| SCHEMBL21315444 | 0.68 | ALDH1A1 (0.38) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL8845448 | 0.67 | MEN1 (0.43) | MEN1KMT2APOLBBRCA1HSD17B10 | |
| SCHEMBL20099452 | 0.66 | CRHBP (0.44) | MEN1KMT2APOLBMAOATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219632-A2 | POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | Johnson & Johnson Vision Care, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-3759171-B9 | AN OPHTHALMIC DEVICE COMPRISING POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE (US) | 2023-05-24 | — | — | EP | disclosed |
| EP-3759171-B1 | AN OPHTHALMIC DEVICE COMPRISING POLYMERIZABLE ABSORBERS OF UV AND HIGH ENERGY VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE (US) | 2023-02-22 | — | — | EP | disclosed |