Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19624856 | 0.88 | RAB9A (0.42) | HPGDSATMTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL19544473 | 0.77 | SCN9A (0.51) | HPGDSTP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL19544753 | 0.72 | HPGDS (0.46) | HPGDSSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL19544895 | 0.71 | KDM4E (0.44) | HPGDSSMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL19624962 | 0.69 | RAB9A (0.41) | ATMTP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL19545219 | 0.68 | MAPT (0.47) | TP53SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL19624888 | 0.67 | ALDH1A1 (0.40) | FNTAFNTBHPGDSSMN1; SMN2ALDH1A1 | |
| SCHEMBL19544636 | 0.67 | KDM4E (0.39) | HPGDSTP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL19544896 | 0.67 | NPSR1 (0.42) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL1456158 | 0.67 | KMT2A (0.53) | TP53SMN1; SMN2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3246317-B1 | BTK INHIBITOR | HUBEI BIO PHARMACEUTICAL INDUSTRIAL TECH INSTITUTE INC (CN) | 2023-02-22 | — | — | EP | disclosed |