SCHEMBL25060702

SCHEMBL25060702

O=c1c2cccc3c2-c2c1ccc(Br)c2c3=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.35
▸ KDM4E B2RXH2 3/20 0.35
▸ HPGD P15428 3/20 0.35
▸ MAPT P10636 2/20 0.35
▸ MEN1 O00255 1/20 0.35
▸ APEX1 P27695 1/20 0.35
▸ RECQL P46063 1/20 0.35
▸ BLM P54132 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ CYP1B1 Q16678 4/20 0.34
▸ CCNE2 O96020 2/20 0.34
▸ CDK4 P11802 2/20 0.34
▸ CCND1 P24385 2/20 0.34
▸ CCNE1 P24864 2/20 0.34
▸ CDK2 P24941 2/20 0.34
▸ CAMK2B Q13554 2/20 0.34
▸ CAMK2G Q13555 2/20 0.34
▸ CAMK2D Q13557 2/20 0.34
▸ CAMK2A Q9UQM7 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12319890 0.82 KDM4E (0.39) ALDH1A1KDM4EHPGDMAPTMEN1
SCHEMBL5420063 0.76 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDMAPTTDP1
SCHEMBL31675099 0.76 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDMAPTTDP1
SCHEMBL26463343 0.76 KDM4E (0.33) ALDH1A1KDM4EHPGDMAPTMEN1
SCHEMBL26464370 0.75 MAPT (0.38) ALDH1A1KDM4EHPGDMAPTMEN1
SCHEMBL19164105 0.71 PARP1 (0.41) ALDH1A1KDM4EHPGDMAPTMEN1
SCHEMBL1445657 0.71 MAOA (0.39) ALDH1A1KDM4EHPGDMAPTTDP1
SCHEMBL29365936 0.71 MAOA (0.39) ALDH1A1KDM4EHPGDMAPTTDP1
SCHEMBL29897736 0.71 CYP1B1 (0.34) ALDH1A1KDM4EHPGDMAPTCYP1B1
SCHEMBL30606655 0.71 CYP1B1 (0.34) ALDH1A1KDM4EHPGDMAPTCYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230137446-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIAL, PREPARING METHOD THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-05-04 — — US disclosed
US-20230137446-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIAL, PREPARING METHOD THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-05-04 — — US disclosed
EP-4137482-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, PREPARATION METHOD THEREFOR AND ORGANIC ELECTROLUMINESCENT DEVICE Wuhan China Star Optoelectronics Semiconductor Display Technology Co., Ltd. (CN) 2023-02-22 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230137446-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIAL, PREPARING METHOD THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE DNTT, CD69, DUT ALDH1A1 350/4885KDM4E 4140/4885HPGD 2157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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