Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262642 | 0.98 | LIPG (0.53) | LIPGADRA2BADRA2CNR1H2NR1H3 | |
| SCHEMBL29265284 | 0.98 | LIPG (0.53) | LIPGADRA2BADRA2CNR1H2NR1H3 | |
| SCHEMBL2698254 | 0.94 | ADRA2B (0.45) | LIPGADRA2BADRA2CARPOLB | |
| SCHEMBL8679853 | 0.88 | ADRA2B (0.53) | ADRA2BADRA2CARPOLBMEN1 | |
| SCHEMBL10408672 | 0.87 | LIPG (0.49) | LIPGADRA2BADRA2CNR1H2NR1H3 | |
| SCHEMBL10409294 | 0.85 | LIPG (0.51) | LIPGNR1H2NR1H3PLK1POLB | |
| SCHEMBL5253208 | 0.85 | LIPG (0.47) | LIPGADRA2BADRA2CNR1H2NR1H3 | |
| SCHEMBL4557996 | 0.85 | LIPG (0.51) | LIPGNR1H2NR1H3PLK1POLB | |
| SCHEMBL8283669 | 0.83 | POLB (0.41) | LIPGADRA2BADRA2CARPOLB | |
| SCHEMBL8761186 | 0.83 | ADRA2B (0.40) | ADRA2BADRA2CARPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230060004-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. | 2023-02-23 | — | — | US | disclosed |
| CN-109912467-A | A kind of synthetic method of 2- aryl phenylethylamine derivative | 南昌航空大学 | 2019-06-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230060004-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | DGKG, DGKB, DGKK | LIPG 217/4885ADRA2B 2859/4885ADRA2C 2609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.