Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.40 |
| ▸ | NAPEPLD | Q6IQ20 | 2/20 | 0.39 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25063138 | 0.92 | ALDH1A1 (0.36) | ALDH1A1KDM4ELMNAHPGDALOX15 | |
| SCHEMBL23304372 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNAHPGDALOX15 | |
| SCHEMBL5247155 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNAHPGDALOX15 | |
| SCHEMBL21299950 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KDM4ELMNAHPGDALOX15 | |
| SCHEMBL23304407 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNAHSD17B10GAA | |
| SCHEMBL23304380 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL30060484 | 0.80 | PIK3CA (0.53) | ALDH1A1KDM4ELMNAHPGDALOX15 | |
| SCHEMBL27172385 | 0.80 | PIK3CA (0.53) | ALDH1A1KDM4ELMNAHPGDALOX15 | |
| SCHEMBL23684985 | 0.79 | RBP4 (0.41) | ALDH1A1KDM4EGAAMEN1THRB | |
| SCHEMBL23684560 | 0.78 | RAD52 (0.40) | ALDH1A1KDM4ELMNAHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230054084-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230054084-A1 | COMPOUNDS AND METHODS OF USE | XDH, LPXN, F12 | ALDH1A1 414/4885KDM4E 3468/4885LMNA 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.