Spiromesifen

Spiromesifen

SCHEMBL25068

Cc1cc(C)c(C2=C(OC(=O)CC(C)(C)C)C3(CCCC3)OC2=O)c(C)c1

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
TP53 P04637 2/20 0.30
MAPT P10636 2/20 0.30
POLB P06746 2/20 0.30
LMNA P02545 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Spiromesifen SCHEMBL4338518 0.95
SCHEMBL3433027 0.92 THRB (0.35) THRBTP53MAPTPOLBLMNA
SCHEMBL11986869 0.90 THRB (0.32) THRBTP53MAPTPOLB
SCHEMBL11986872 0.90 POLB (0.30) POLB
SCHEMBL14464600 0.90 POLB (0.32) THRBTP53POLBLMNAALDH1A1
Spiromesifen SCHEMBL19032812 0.89
SCHEMBL11986868 0.89
SCHEMBL782178 0.88
SCHEMBL15693409 0.87 ALDH1A1 (0.34) THRBTP53MAPTPOLBLMNA
SCHEMBL18559766 0.83 TSHR (0.34) THRBTP53MAPTLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 20362 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4734762-A1 BAIT COMPOSITIONS FMC Corporation (US) 2026-05-06 EP claimed
EP-4719059-A1 INCREASED PALATABILITY OF INSECTICIDAL INSECT BAITS Bio Logic Crop Science, S.L. (ES) 2026-04-08 EP claimed
US-20260090546-A1 COMBINATIONS OF KETO-ENOL INSECTICIDES ADAMA MAKHTESHIM LTD. (IL) 2026-04-02 US claimed
US-20260083130-A1 NOVEL SULFONATE BENZAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC CORP (US) 2026-03-26 US claimed
US-20260083129-A1 PYRAZOLE AMIDE INSECTICIDES FMC CORP (US) 2026-03-26 US claimed
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 EP claimed
EP-4709166-A1 NOVEL INSECTICIDAL MIXTURES FOR CONTROLLING AND PROTECTING CROPS ADAMA MAKHTESHIM LTD. (IL) 2026-03-18 EP claimed
EP-4709163-A1 MIXTURE COMBINATIONS FOR CROP PROTECTION ADAMA MAKHTESHIM LTD. (IL) 2026-03-18 EP claimed
US-12568969-B2 Pyridine compounds for controlling invertebrate pests FMC CORPORATION (US) 2026-03-10 US claimed
CN-121586714-A Connected bicyclic compounds for control and combating invertebrate pests FMC公司 2026-02-27 CN claimed
WO-2005118552-A2 ANTHRANILAMIDE INSECTICIDES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-12-15 WO claimed
EP-1599463-A1 CYANO ANTHRANILAMIDE INSECTICIDES E.I. du Pont de Nemours and Company (US) 2005-11-30 EP claimed
WO-2005080327-A1 INSECTICIDAL AND NEMATICIDAL DIFLUOROALKENE DERIVATIVES E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-09-01 WO claimed
WO-2005074685-A1 PLANT PROTECTION COMPOSITIONS AND USE THEREOF BAYER CROPSCIENCE GMBH (DE) 2005-08-18 WO claimed
WO-2005053407-A1 PESTICIDALLY ACTIVE COMBINATIONS SYNGENTA PARTICIPATIONS AG (CH) 2005-06-16 WO claimed
US-20050065197-A1 Thiazole derivatives with fungicidal activity ISAGRO RICERCA S.R.L. (IT) 2005-03-24 US claimed
EP-1453817-A1 THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY Isagro Ricerca S.r.l. (IT) 2004-09-08 EP claimed
WO-2004067528-A1 CYANO ANTHRANILAMIDE INSECTICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-08-12 WO claimed
US-20030198659-A1 Fibrous pest control CORNELL RESEARCH FOUNDATION, INC. 2003-10-23 US claimed
WO-2003050096-A1 THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY ISAGRO RICERCA S.R.L. (IT) 2003-06-19 WO claimed