Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Spiromesifen SCHEMBL25068 | 0.92 | THRB (0.31) | THRBLMNAALDH1A1TP53POLB | |
| SCHEMBL14464600 | 0.89 | POLB (0.32) | THRBLMNAALDH1A1TP53POLB | |
| Spiromesifen SCHEMBL4338518 | 0.88 | — | — | |
| SCHEMBL11986869 | 0.83 | THRB (0.32) | THRBTP53POLBMAPT | |
| Spiromesifen SCHEMBL19032812 | 0.82 | — | — | |
| SCHEMBL16511965 | 0.81 | MAPT (0.34) | THRBLMNATP53POLBMAPT | |
| SCHEMBL11986868 | 0.81 | — | — | |
| SCHEMBL782178 | 0.81 | — | — | |
| SCHEMBL16511689 | 0.80 | MAPT (0.36) | THRBLMNATP53POLBMAPT | |
| SCHEMBL15693409 | 0.80 | ALDH1A1 (0.34) | THRBLMNAALDH1A1TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8816097-B2 | Active ingredient combinations having insecticide and acaricide properties | BAYER CROPSCIENCE AG (DE) | 2014-08-26 | — | — | US | disclosed |
| US-8816097-B2 | Active ingredient combinations having insecticide and acaricide properties | BAYER CROPSCIENCE AG (DE) | 2014-08-26 | — | — | US | disclosed |
| US-20120094829-A1 | Active Compound Combinations Having Insecticidal and Acaricidal Properties | BAYER CROPSCIENCE AG (DE) | 2012-04-19 | — | — | US | disclosed |
| US-20100130578-A1 | ACTIVE INGREDIENT COMBINATIONS HAVING INSECTICIDE AND ACARICIDE PROPERTIES | BAYER CROPSCIENCE AG | 2010-05-27 | — | — | US | disclosed |
| US-20100130578-A1 | ACTIVE INGREDIENT COMBINATIONS HAVING INSECTICIDE AND ACARICIDE PROPERTIES | BAYER CROPSCIENCE AG | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130578-A1 | ACTIVE INGREDIENT COMBINATIONS HAVING INSECTICIDE AND ACARICIDE PROPERTIES | ACHE, DDT, ACACA | THRB 2765/4885LMNA 3103/4885ALDH1A1 143/4885 |
| US-20120094829-A1 | Active Compound Combinations Having Insecticidal and Acaricidal Properties | ACHE, CA3, CACNA1G | THRB 346/4885LMNA 3444/4885ALDH1A1 663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.