Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.61 |
| ▸ | HTR1A | P08908 | 2/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.61 |
| ▸ | DRD1 | P21728 | 2/20 | 0.61 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.61 |
| ▸ | DRD3 | P35462 | 2/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16757326 | 0.83 | CYP2D6 (0.66) | CYP2D6CYP19A1SMN1; SMN2CHRM2HTR1A | |
| SCHEMBL7668121 | 0.82 | CHRM2 (0.83) | CYP2D6CYP19A1SMN1; SMN2CHRM2HTR1A | |
| SCHEMBL2056217 | 0.80 | CHRM2 (0.86) | CYP2D6CYP19A1SMN1; SMN2CHRM2HTR1A | |
| SCHEMBL25068897 | 0.80 | CHRM2 (0.64) | CYP2D6CYP19A1SMN1; SMN2CHRM2HTR1A | |
| SCHEMBL13309489 | 0.77 | CYP2D6 (0.71) | CYP2D6CYP19A1SMN1; SMN2CHRM2HTR1A | |
| SCHEMBL3263282 | 0.77 | GPX4 (0.58) | CYP2D6CYP19A1SMN1; SMN2CHRM2HTR1A | |
| SCHEMBL13309488 | 0.77 | CYP2D6 (0.71) | CYP2D6CYP19A1SMN1; SMN2CHRM2HTR1A | |
| SCHEMBL6824843 | 0.77 | CYP2D6 (0.71) | CYP2D6CYP19A1SMN1; SMN2CHRM2HTR1A | |
| Homochlorcyclizine SCHEMBL30402 | 0.77 | DRD3 (1.00) | CYP2D6SMN1; SMN2CHRM2HTR1AADRA2A | |
| SCHEMBL1137956 | 0.76 | CYP2D6 (1.00) | CYP2D6CYP19A1SMN1; SMN2CHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230055961-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | DUNAD THERAPEUTICS LTD. (GB) | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230055961-A1 | PENTAFLUOROBENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | FURIN, PFAS, CFTR | CYP2D6 129/4885CYP19A1 1200/4885SMN1; SMN2 566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.