Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 6/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.33 |
| ▸ | VCP | P55072 | 2/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | GCKR | Q14397 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GRK2 | P25098 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25738984 | 0.79 | LMNA (0.43) | TAS2R14VCPPOLBKDM4EALDH1A1 | |
| SCHEMBL25073051 | 0.78 | ALDH1A1 (0.44) | TAS2R14PTPN11DGAT1VCPALDH1A1 | |
| SCHEMBL25734897 | 0.78 | ALDH1A1 (0.44) | TAS2R14PTPN11DGAT1VCPALDH1A1 | |
| SCHEMBL25072802 | 0.78 | ALDH1A1 (0.44) | TAS2R14PTPN11DGAT1VCPALDH1A1 | |
| SCHEMBL25072808 | 0.76 | POLB (0.50) | POLBKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL25072803 | 0.71 | MAPT (0.61) | POLBALDH1A1MAPTNPSR1KMT2A | |
| SCHEMBL25072797 | 0.66 | PTPN11 (0.40) | PTPN11GCKGCKRKDM4ENPC1 | |
| SCHEMBL25073050 | 0.66 | CA2 (0.45) | PTPN11GCKGCKRKDM4ENPC1 | |
| SCHEMBL25072475 | 0.66 | PTPN11 (0.42) | PTPN11GCKGCKRKDM4ENPC1 | |
| SCHEMBL25073028 | 0.63 | PTPN11 (0.44) | PTPN11GCKGCKRRORCPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023310-A1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. (US) | 2023-02-23 | — | — | WO | disclosed |