Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31746891 | 1.00 | RXFP1 (0.39) | RXFP1NOTUMTRPA1TAS2R14TRPV1 | |
| SCHEMBL25073878 | 0.92 | NOTUM (0.39) | RXFP1NOTUMTRPA1TRPV1NTRK1 | |
| SCHEMBL31746925 | 0.92 | NOTUM (0.39) | RXFP1NOTUMTRPA1TRPV1NTRK1 | |
| SCHEMBL31746947 | 0.92 | RXFP1 (0.47) | RXFP1NOTUMMAPTHTTSMN1; SMN2 | |
| SCHEMBL25073887 | 0.92 | RXFP1 (0.47) | RXFP1NOTUMMAPTHTTSMN1; SMN2 | |
| SCHEMBL25073757 | 0.92 | TRPA1 (0.47) | RXFP1NOTUMTRPA1TRPV1MAPT | |
| SCHEMBL31746896 | 0.92 | TRPA1 (0.47) | RXFP1NOTUMTRPA1TRPV1MAPT | |
| SCHEMBL25073881 | 0.89 | RXFP1 (0.41) | RXFP1TRPA1TAS2R14NTRK1MAPT | |
| SCHEMBL31746957 | 0.89 | RXFP1 (0.41) | RXFP1TRPA1TAS2R14NTRK1MAPT | |
| SCHEMBL25073855 | 0.88 | NOTUM (0.42) | NOTUMNTRK1SYKMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023021278-A1 | PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 | REDX PHARMA PLC (GB) | 2023-02-23 | — | — | WO | disclosed |