Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25073878 | 1.00 | NOTUM (0.39) | NOTUMTRPA1NLRP3NTSR1NTRK1 | |
| SCHEMBL25073752 | 0.92 | RXFP1 (0.39) | NOTUMTRPA1NLRP3NTSR1NTRK1 | |
| SCHEMBL31746891 | 0.92 | RXFP1 (0.39) | NOTUMTRPA1NLRP3NTSR1NTRK1 | |
| SCHEMBL25073877 | 0.92 | NOTUM (0.42) | NOTUMTRPA1NLRP3ALDH1A1RAB9A | |
| SCHEMBL30279170 | 0.92 | NOTUM (0.42) | NOTUMTRPA1NLRP3ALDH1A1RAB9A | |
| SCHEMBL25073880 | 0.92 | TRPA1 (0.41) | NOTUMTRPA1NLRP3NTSR1ALDH1A1 | |
| SCHEMBL31746956 | 0.88 | NOTUM (0.42) | NOTUMNLRP3NTSR1NTRK1ALDH1A1 | |
| SCHEMBL25073855 | 0.88 | NOTUM (0.42) | NOTUMNLRP3NTSR1NTRK1ALDH1A1 | |
| SCHEMBL31746961 | 0.87 | NOTUM (0.43) | NOTUMNTSR1NTRK1ALDH1A1MAPT | |
| SCHEMBL25073750 | 0.87 | NOTUM (0.43) | NOTUMNTSR1NTRK1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387963-B1 | PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 | REDX PHARMA LTD (GB) | 2025-12-24 | — | — | EP | disclosed |