Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25073869 | 1.00 | KMT2A (0.42) | KMT2AMIFPPARGPPARDPPARA | |
| SCHEMBL25073871 | 0.82 | KDM4E (0.43) | NPC1KDM4EALDH1A1POLB | |
| SCHEMBL30279192 | 0.82 | KDM4E (0.43) | NPC1KDM4EALDH1A1POLB | |
| SCHEMBL30279156 | 0.80 | PSMB1 (0.41) | KMT2APSMB1PSMB5MEN1NPC1 | |
| SCHEMBL25073870 | 0.80 | PSMB1 (0.41) | KMT2APSMB1PSMB5MEN1NPC1 | |
| SCHEMBL25073776 | 0.79 | KMT2A (0.51) | KMT2AITGB3ITGA2BPSMB1PSMB5 | |
| SCHEMBL30279190 | 0.79 | KMT2A (0.51) | KMT2AITGB3ITGA2BPSMB1PSMB5 | |
| SCHEMBL31096322 | 0.71 | KMT2A (0.42) | KMT2AMIFPPARGPPARDPPARA | |
| SCHEMBL23850234 | 0.71 | KMT2A (0.42) | KMT2AMIFPPARGPPARDPPARA | |
| SCHEMBL1576340 | 0.71 | KMT2A (0.60) | KMT2APPARGPPARDPPARAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387963-A1 | PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 | Redx Pharma Limited (GB) | 2024-06-26 | — | — | EP | disclosed |
| CN-117813297-A | Phenyl and pyridopyrazole derivatives as DDR1 inhibitors | 莱德克斯制药公共有限公司 | 2024-04-02 | — | — | CN | disclosed |
| WO-2023021278-A1 | PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 | REDX PHARMA PLC (GB) | 2023-02-23 | — | — | WO | disclosed |