Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 3/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 13/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25073923 | 0.86 | ELANE (0.53) | PSMB1PSMB5GRIN2BELANEKDM4E | |
| SCHEMBL31746932 | 0.86 | ELANE (0.53) | PSMB1PSMB5GRIN2BELANEKDM4E | |
| SCHEMBL30279167 | 0.81 | KDM4E (0.45) | PSMB1PSMB5KDM4E | |
| SCHEMBL30279166 | 0.81 | KDM4E (0.45) | PSMB1PSMB5KDM4E | |
| SCHEMBL25073774 | 0.81 | KDM4E (0.45) | PSMB1PSMB5KDM4E | |
| SCHEMBL25073874 | 0.76 | NLRP3 (0.51) | KDM4E | |
| SCHEMBL31162542 | 0.76 | NLRP3 (0.51) | KDM4E | |
| SCHEMBL25073776 | 0.76 | KMT2A (0.51) | PSMB1PSMB5KDM4E | |
| SCHEMBL30279190 | 0.76 | KMT2A (0.51) | PSMB1PSMB5KDM4E | |
| SCHEMBL25073633 | 0.74 | GRIN2B (0.43) | PSMB1PSMB5GRIN2BELANENTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023021278-A1 | PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 | REDX PHARMA PLC (GB) | 2023-02-23 | — | — | WO | disclosed |